Medscape - Indication-specific dosing for Precedex, (dexmedetomidine), Load: 1 mcg/kg IV over 10 minutes; loading dose may not be required for adults converted from other sedative therapy Indicated for sedation of nonintubated patients before and/or during surgical and other . Peak plasma: 0.3-1.5 ng/mL.
For adult patients, PRECEDEX® may be initiated with a loading infusion of 1 ( one) . (AUC0-24h) at this dose level was less than anticipated at the maximum .
Adult patients receiving dexmedetomidine were included in our study. rate at the endpoint is no more than half of the maximum infusion rate.